Tuesday 27 March 2012

That hill you climb at the start...

I feel like I am on that hill you climb before the first downhill on a rollercoaster, where you build all the momentum to get you through all the twists and turns and loop de loops ahead.  Have you ever anticipated something?  I honestly have the same feeling I did before I got engaged to my handsome hub!  This feeling of expectation, but not knowing when that expectation will be fulfilled

I was waiting for 5 days.  Waiting for my cycle to start. Waiting for the safety bar to drop over my head and the ride to start.  I was 5 days late.  I am rarely late! This would usually get me very excited (If I am 5 hours late I run off to the pharmacy to buy a pregnancy test) except we have had a scan already at the new Fertility Specialist and the news wasn’t exactly encouraging...

We went to Bio Art.  Where Medfem was calm and serene and predictable environment, Bio Art was not. There were so many people there, that there were not enough waiting room chairs to sit on, and there were couples and nurses and people just everywhere.  Initially the chaos really confused me and got me worked up but one of the nurses explained that one of the 2 doctors was not in and so the other was doing all the routine scans, procedures as well as the booked appointments.

For those of you not in fertility treatment, let me take a moment to explain how this works.  If you are in treatment there are certain days of your cycle that you need to go and have a scan on, 9, 11, 13 or the insemination procedure on day 14 or 15... So you don’t book appointments for these days, you just go in first thing (7am) and the doctors do all the scans first, and any procedures that have to be done, like inseminations or embryo transplants before they start with their booked appointments.
So when one out of two doctors is out, you can imagine what chaos ensues! Anyway, moving on....

What a lovely, and experienced, new doctor Dr C is! He picked up on more and it now looks like there may be more "wrong with me" than previously thought.  He gave lots of attention to hubby's results, which he (hub) liked, as the other Dr has often just glossed over them. Of interest to the Doc was the low morphology and a high CMA 3 count, where the other Doc has always been more interested in the motility issue.  CMA 3 is the measure of immature DNA in the nucleus of the sperm cell.  Although it’s high, it’s not hopelessly out of range, and Dr C seemed to think that hubby could get me pregnant naturally.

BUT...

Dr C scanned and said that it looks like there were implantations this month :-(and seeing as I was a day late they gave me a Home Pregnancy Test - was negative.
He also thinks that I am still having strong immune responses to implantation of the embryos brought on by the endometriosis, and losing them before they really even have a chance, although we are not sure we actually want that embryo’s to implant, because we think they may be blighted – possibly a combination of my poor quality eggs plus hubby's poor immature DNA in his sperm is giving us dodgy embryos, which are implanting but probably wouldn’t make it past 6 or 8 weeks anyway if it weren’t for the immune response - he reckons I would have recurrent miscarriages if we treated just the immune response and continued to try naturally.

On the up side, he said that a pregnancy would sort me out - it stops the endometriosis and all its nonsense in its tracks, so if you have had endometrial complications is highly likely that once you get pregnant and break the cycle you don’t struggle with endometriosis again.
It will be interesting to actually see what the egg quality is like once he gets them out, and see if his suspicions are correct.

So the Plan of action is as follows, as soon as my cycle shows up I start the Birth Control Pill, then on Day 21 I will start the Long Protocol IVF cycle. We will definitely have to ICSI. (Inject the sperm into the egg). We are also chucking in intravenous Intralipids just to distract my immune system while my embryos implant. Dr recons we will be lucky to have a successful fertilisation of 60% of the eggs, but recons that there may not be too much to put back, best case 2 or 3, given the DNA issues. If we have 2 we will definitely put 2 back.

We were then chased down the corridor by one of the nurses for blood tests and a small chat about the rest of the procedure. The nurse also did a Beta quant (pregnancy test) and promised to call me on Friday if there was anything worth reporting.... no phone call
.
I am on a strict dietary regimen to try and improve the egg quality:
No alcohol, No Sugar, No refined Carbs, NO carbs or fruit after 5 pm, No white flours, No Saturated fats (NO fun!). Let’s be honest the hill is not the fun part of the rollercoaster!
Lots of fresh fruit, Veg, Monosaturated fats, 3l water a day, lean protein, fish, legumes, nuts and low fat dairy.
The dietician is a little worried that I may become underweight for what we are trying to achieve - I have already lost 7kgs since September, so we will monitor that and make sure I don’t become too underweight for what we are trying to achieve

So I guess my prayer needs are for good quality eggies, and that we will have some great embryos to put back and that they will (both?) stick!

I paid the deposit on the treatment, I wondered to myself if this was what it feels like to buy an engagement ring?  That nervous sense of expectation, the guy hope the outcome is favourable but there is a chance it may not be, and with that in mind he spends thousands of rands on a diamond ring? 

We have a meeting with the nurse next week to pick up all the meds and get a small tutorial on how each one is injected. So I will write another update after that milestone.

We are all buckled in - I am so excited - let the rollercoaster ride begin!

 

Tuesday 20 March 2012

Hello Autumn!

Let it be known - I am not a winter person! In fact there is something so utterly depressing to me about the imminent change in season that the only thing that gets me through winter is knowing that I have a wonderful summer wardrobe to look forward to as I take out the winter clothes from the suit case at the top of my cupboard and hang all the winter clothes and pack all the summer clothes.

Usually I wait as long as possible, denying the presence if the morning chill and pretending that there is still a piece of summer left. This year I am so over denial! Today really IS the first day of autumn! The weather man said so - it is time!

It is also time for us to admit to ourselves that we are going to need more help to get this conception thing right. The comment made by the embryologist while preparing our sample was that these sperm, although much improved, are "IVF sperm". I suppose that was one of the reasons for me not being too surprised when the AI didn’t work. It’s definitely the reason I don’t want to bother with AI again - It felt like wasted time energy, emotion and money at the end of it all.

I have also come to accept that we cannot continue on at Medfem... Thety have moved us in the right direction, found and eliminated the Endometriosis, sorted out the low progesterone levels, and provided quite a stable nurtuting environment in which to undergo all the tests and start wading our way into the infertility waters. As much as I like the place and respect the skill and expertise of the doctors and embryologists there, and I do think that it is a first class facility, and I would stay if we could, but we have just had to face the facts - it’s too expensive for us!

We move to a clinic, BioArt that will do the same treatment for almost half the price, and amongst the online fertility community is widely respected and is achieving really good results.  Lots of positives. I see the new fertility specialist this week. I truly cannot wait - I am more excited about this that I am about my birthday which is round the corner too.

On the miracle side of things, we have had some miraculous financial donations come through specifically for treatment, and some extra bonus money from work which makes an IVF cycle immediately possible.  I am always amazed at how God honours our faithfulness!  At the end on Jan, we were challenged to give a offering, larger than something we would usually consider, to missionary friends of ours living in an eastern Country.  We were challenged and hesitant, but we did it anyway.  God restored that offering to us in abundance - we have not been left out of pocket at all! 

This is not the only example of how he has provided for this IVF cycle.  I strongly believe we need to go through with this.  That this whole weird, sad, frustrating journey is purposeful and I foresee several "ahhaaa" moments in the years to come as I realise how God is using it. (I DO NOT see them yet - this is a faith statement.

So maybe, come spring in September, I won’t be unpacking the summer wardrobe. I won’t be able to because all my size 12 outfits don’t fit, I am in maternity wear!  I really do have a lot to look forward to this winter - bring it on! 

Right - I am off to do the wardrobe swop